Dr Mars Skae
Consultant Paediatric Endocrinologist
MB ChB (Sheffield), MRCPH, MPhil (UoM
Congenital Hyperinsulinism, Disorders of sexual Development (DSD), Transition and adolescent endocrinology, Metabolic bone medicine including skeletal dysplasias
A Malaysian by birth, Dr Skae moved to England to read medicine at Sheffield University and graduated in 1998. She obtained membership to the Royal College of Paediatrics and Child Health and completed her general paediatric training in Manchester. Dr Skae undertook a Clinical Research Fellowship in congenital hyperinsulinism at the Royal Manchester Children’s Hospital (RMCH) and completed an MPhil in Physiology at the University of Manchester (UoM) with Prof.Dunne and Dr.Cosgrove. She was later appointed to a consultant post in Paediatric Endocrinology at the RMCH. Dr Skae has also been developed interests in metabolic bone diseases with particular focus on skeletal dysplasias and is also currently the lead for DSD. In addition to her clinical role, she is actively involved in the training of junior medical staff and medical students and maintains a keen interest in research through a successful Research for Patient Benefit Grant in Experimental Medicine.
Selected recent publications
- Adjacent mutations in the gating loop of Kir6.2 produce
neonatal diabetes and hyperinsulinism.
Kenju Shimomura, Sarah E. Flanagan, Brittany Zadek, Mark Lethby,
Lejla Zubcevic Christophe AJ Girard Oliver Petz, Ritika R Kapoor,
Roope Manniko, Khalid Hussain, Mars Skae, Peter Clayton, Andrew
Hattersley, Sian Ellard and Frances M Ashcroft
EMBO Mol Med.2009; Jun 1(3):166-77.
- The Effect of Biopsy Positive Silent Celiac Disease and
Treatment with a Gluten-Free Diet on Growth and Glycaemic Control
in Children with Type 1 Diabetes.
Shichao Sun, Radhika Puttha, Sarah Ghezaiel, Mars Skae, Chris
Cooper and Rakesh Amin - on behalf of the North West England
Paediatric Diabetes Network
Diabetic Medicine. 2009Dec;26(12):1250-4.
Banerjee I, Skae M, Flanagan SE, Rigby L, Patel L, Didi M, Blair
J, Ehtisham S, Ellard S, Cosgrove KE, Dunne MJ, Clayton PE. Eur J
Endocrinol. 2011 May;164(5):733-40.
Powell PD, Bellanné-Chantelot C, Flanagan SE, Ellard S, Rooman
R, Hussain K, Skae M, Clayton P, de Lonlay P, Dunne MJ, Cosgrove
KE. Diabetes. 2011 Apr;60(4):1223-8.
Hanson D, Murray PG, O'Sullivan J, Urquhart J, Daly S, Bhaskar
SS, Biesecker LG, Skae M, Smith C, Cole T, Kirk J, Chandler K,
Kingston H, Donnai D, Clayton PE, Black GC. Am J Hum Genet. 2011