Gynaecological cytology FAQs
These are some of the most frequently asked questions about
using our gynaecological cytology service.
If your question is not answered here, try the gynaecological cytology user
guide or contact us.
(Last updated March 30th 2016)
Question 1: How do I get consumables or request forms?
The laboratory will deliver a 12-month supply of kits to each
practice/clinic. If there are any issues relating to the provision
of LBC kits, contact the laboratory on 0161 276 5172.
To order paper request forms, contact us on 0161 276 5172.
Alternatively, the electronic HMR101 form
can be used.
Question 2: How do I collect a cervical sample?
The Manchester Cytology Centre processes and reports SurePath®
cervical LBC samples. These should only be collected by trained
Training in sample collection for primary care staff is
available on request from the cytology training leads at the local
Primary Care Trust.
The cytology training lead can also arrange for three-yearly
update training for sample takers so they remain aware of
developments within the cervical screening programme and to
See instructions on sample collection.
Question 3: How do I manage my patients?
Samples taken from women within the NHSCSP screening age ranges
that have adequate cellularity can be tested for high-risk human
Women are ineligible if they are below the minimum age for
screening or if their sample contains insufficient squamous cells
as scanty samples may yield a false negative HR-HPV result.
Question 4: What is Sentinel Site?
Experience gained from the HPV triage pilots, in which the
Manchester Cytology Centre was involved, has enabled the programme
to move forward with HPV triage of borderline changes and mild
Testing will now be introduced to the programme. This means that
any women who have a cervical screening test result of borderline
changes or mild dyskaryosis will automatically have an HPV test
performed on their sample (where HPV triage is implemented).
If HPV is found they will be referred for colposcopy and if HPV
is not found they will be returned to routine screening every three
or five years depending on their age.
In addition to HPV triage, an HPV 'Test of Cure' is being
introduced for women who have undergone treatment for CIN.
This means that HPV tests will be carried out on samples from
women who have a normal screening test result after having
treatment for CIN.
If HPV is not found then the women will not be recalled for
screening for a further three years. If, however, HPV is found or
the screening test does show an abnormality the women will be
referred again to colposcopy.
For more information see the NHSCSP webpage on the
evaluation of Sentinel Sites for HPV triage and test of
Question 5: What is direct referral?
Manchester Cytology Centre (MCC) has well-established
systems and several years of experience with direct referral to
We currently operate a direct referral programme to 13
colposcopy units and liaise with LASCA, Manchester and North
Cumbria screening agencies to generate direct referral result
The direct referral policy documents produced by MCC in
collaboration with the colposcopy clinics incorporate a protocol
for the allocation of appointments based on the cytology
This information is provided to the colposcopy clinic by
the MCC, via the screening agencies and allows efficient use of
appointments to ensure women at highest risk get the earliest