The availability of 2nd and 3rd plus generation drugs etc, their
appropriate usage, and the occurrence of resistance to therapy due
to the presence of ABL kinase domain mutations, requires additional
We can send appropriate samples for an ABL kinase domain
mutation screen to our collaborators, on behalf of referrers.
The current testing is applied to mutations occurring in the ABL
kinase gene. This does not exclude other mechanisms of resistance
that have been documented.