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Tests under evaluation/consideration

Tests under evaluation

  • BCR-ABL mutation screen for the ABL kinase domain to provide information on drug resistance and to indicate changes that may be required in therapy based upon the mutation indicated.
  • CALR mutations

Tests under consideration

  • JAK2 exon 12
  • CEBP-alpha in AML as well as a consortia of panel genes to risk profile at diagnosis
  • ALL mutation screening for paediatric patients.
  • Other new and established target genes as required for the molecular work up indicated by standard and best practice.
  • Next generation sequencing to assess increased panels of genes for diagnostic profiling to risk stratify patients for specific treatment options.