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Electron Microscopy specimen processing and preparation for examination

Tissue samples are each assessed for appropriate size, dissected (if necessary) and then processed into resin blocks.
Semi-thin sections are then cut from the blocks to identify those with suitable regions of interest. Those showing regions of interest are cut to produce ultra-thin sections which are subsequently mounted onto copper grids. Grids/sections are then stained ready for examination using the electron microscope.

All material is then archived in accordance with current Royal College of Pathologists guidelines as a minimum.


(Last reviewed 19th June 2018)