Acetylcholine receptor antibody
Acts as a confirmatory test for myasthenia gravis.
Specimen transport: At room temperature
Repeat frequency: At change of clinical
Special precautions: None
Normal reference range: 0 - 0.45nmol/L
Volume and sample type: 7ml clotted blood
Turnaround time (calendar days from sample
receipt to authorised result): Median - 3, 95th percentile - 13
Indications for the test: 90% of patients with
generalised myasthenia gravis and about 60-70% of patients with
ocular myasthenia have detectable AChR antibodies. Can be used to
monitor disease activity, but antibodies may persist in 60% of
patients even if disease is in remission.
The assay also detects antibodies to the fetal form of the AChR
in mother of fetuses with Arthrogryposis multiplex congenital.
Clinical workstation reference: ACH-R Ab
(Last updated October 7th