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Acetylcholine receptor antibody

General information

Acts as a confirmatory test for myasthenia gravis.

Specimen transport: At room temperature

Repeat frequency: At change of clinical symptoms

Special precautions: None

Laboratory information

Normal reference range: 0 - 0.45nmol/L

Volume and sample type: 7ml clotted blood

Method: ELISA

Turnaround time (calendar days from sample receipt to authorised result): Median - 3, 95th percentile - 13

Clinical information

Indications for the test: 90% of patients with generalised myasthenia gravis and about 60-70% of patients with ocular myasthenia have detectable AChR antibodies. Can be used to monitor disease activity, but antibodies may persist in 60% of patients even if disease is in remission.

The assay also detects antibodies to the fetal form of the AChR in mother of fetuses with Arthrogryposis multiplex congenital.


Clinical workstation reference: ACH-R Ab


(Last updated October 7th 2014)