We use cookies to help us improve the website and your experience using it. You may delete and block all cookies from this site at any time. However, please note this may result in parts of the site no longer working correctly. If you continue without changing your settings we will assume you are happy to receive all cookies on this site.


Acetylcholine receptor antibody

General information

Acts as a confirmatory test for myasthenia gravis.

Specimen transport: At room temperature

Repeat frequency: At change of clinical symptoms

Special precautions: None

Laboratory information

Normal reference range: 0 - 0.45nmol/L

Volume and sample type: 7ml clotted blood

Method: ELISA

Turnaround time (calendar days from sample receipt to authorised result): Median - 7

Clinical information

Indications for the test: 90% of patients with generalised myasthenia gravis and about 60-70% of patients with ocular myasthenia have detectable AChR antibodies. Can be used to monitor disease activity, but antibodies may persist in 60% of patients even if disease is in remission.

The assay also detects antibodies to the fetal form of the AChR in mother of fetuses with Arthrogryposis multiplex congenital.


ICE reference: Acetylcholine Receptor Antibodies


(Last updated August 22nd 2018)