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Centromere antibody – refer to ANA panel

General information

Centromere antibody is detected as part of our ANA panel. Centromere is seen in limited systemic sclerosis (CREST syndrome - calcinosis, Raynaud's, oesophageal dysmotility and telangiectasia) and in primary biliary cirrhosis.

Specimen transport: At room temperature

Repeat frequency: On appearance of new symptoms

Special precautions: None

Laboratory information

Normal reference range: <0.9AI

Volume and sample type: 7ml clotted blood

Method: Multiplex flow immunoassay

Turnaround time (calendar days from sample receipt to authorised result): Median - 1, 95th percentile - 4

Clinical information

Indications for the test: Raynaud's phenomenon, CREST syndrome, PBC

Factors affecting the test: None


Clinical workstation reference: ANA


(Last updated October 7th 2014)