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IgE (Total)

General information

Specimen transport: At room temperature

Repeat frequency: At significant change of clinical symptoms

Special precautions: None

Laboratory information

Normal reference range: Age specific (mean ┬▒ 2SD)

Age range Total IgE (kU/L)
0 days to 6 weeks < 5.2
6 weeks to 3 months < 9.2
3 to 6 months < 16.4
6 to 9 months < 22.6
9 to 12 months < 29.2
1 to 2 years < 51.7
2 to 3 years < 72.0
3 to 4 years < 90.0
4 to 5 years < 108.0
5 to 6 years < 126.0
6 to 7 years < 142.0
7 to 8 years < 160.0
8 to 9 years < 176.0
9 to 10 years < 192.0
Above 10 years < 114.0

 

Volume and sample type: 7ml clotted blood, 14ml if multiple tests

Method: Immunoassay (Immunocap® 1000)

Turnaround time (calendar days from sample receipt to authorised result): Median - 2, 95th percentile - 5

Clinical information

Indications for the test: Patients with suspected allergy (atopic disease). Main use of the test is to help interpret specific IgE levels.

Factors affecting the test: Total IgE >3000kU/L increases the incidence of false positive (low level) specific IgE. IgE <30 kU/L associated with false negative specific IgE. Similarly, very low IgE levels (<2.0 kU/L) may indicate an underlying immunodeficiency; measurement of immunoglobulins is recommended.

 

Clinical workstation reference: TOTAL IgE

 

(Last updated October 7th 2014)