IgG subclasses
General information
IgG1, IgG2, IgG3, IgG4
Specimen transport: At room temperature
Repeat frequency: Not within 6 months
Special precautions: None
Laboratory information
Normal reference range: Age and gender
specific
Age |
IgG1 g/l |
IgG2 g/L |
IgG3 g/L |
IgG4 g/L |
0-1 days |
2.9 - 12.6 |
1.1 - 6.6 |
0.2 - 1.4 |
0.05 - 1.4 |
1-2 days |
2.7 - 14.6 |
1.1 - 6.9 |
0.2 - 1.2 |
0.04 - 1.3 |
3-6 days |
2.4 - 11.6 |
<1 - 6.4 |
0.2 - 1.0 |
0.04 - 1.2 |
1-2 weeks |
2.1 - 10.8 |
0.7 - 4.9 |
0.1 - 0.8 |
0.03 - 0.9 |
2-4 weeks |
1.9 - 9.8 |
0.5 - 2.9 |
0.1 - 0.8 |
0.02 - 0.7 |
4-8 weeks |
1.4 - 8.8 |
0.3 - 2.6 |
0.1 - 0.8 |
0.02 - 0.5 |
8-16 weeks |
1.2 - 8.8 |
0.3 - 2.6 |
0.1 - <1 |
0.02 - 0.3 |
16-26 weeks |
1.6 - 9.8 |
0.4 - 2.3 |
0.1 - <1 |
0.03 - 0.7 |
6-12 months |
1.8 - 10.8 |
0.5 - 2.3 |
0.1 - 1.2 |
0.02 - 1.4 |
1-4 years |
2.4 - 12.6 |
0.6 - 2.6 |
0.2 - 1.4 |
0.02 - 1.8 |
4-8 years |
3.4 - 14.6 |
0.6 - 2.9 |
0.2 - 1.3 |
0.02 - 1.8 |
8-12 years |
3.4 - 11.6 |
0.7 - 4.4 |
0.2 - 2.9 |
0.02 - 1.8 |
12-16 years |
3.4 - 11.6 |
0.8 - 7.8 |
0.2 - 2.8 |
0.03 - 3 |
16-20 years |
3.4 - 11.6 |
1.1 - 6.6 |
Male: 0.2-2.0
Female 0.2-1.3 |
0.05 - 2 |
20-40 years |
2.9 - 12.6 |
1.1 - 6.6 |
0.2 - 1.3 |
0.05 - 2 |
40-50 years |
2.9 - 12.6 |
1.1 - 6.6 |
0.2 - 1.3 |
0.05 - 2 |
50-70 years |
2.9 - 12.6 |
1.1 - 6.6 |
0.2 - 1.3 |
0.05 - 2 |
70-90+ years |
3.9 - 13.6 |
1.1 - 6.6 |
0.2 - 1.3 |
0.05 - 2 |
Volume and sample type: 7ml clotted blood
Method: Nephelometry
Turnaround time (calendar days from sample
receipt to authorised result): Median - 1,. 95th percentile - 5
Clinical information
Indications for the test: History of bacterial
sinopulmonary infection and IgG between 5-16g/L. History of/or
failure to respond to polysaccharide vaccines, pancreatitis
(history of recurrent infections - not viral), or abscesses or
(failure to respond to immunisation) AND (Total IgG < 0.1
g/l).
Samples not meeting these requirements will be rejected.
Factors affecting the test: None
Clinical workstation reference: IgG2 SUBLASS or
IgG4 SUBCLASS
(Last updated October 7th
2014)