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PR3 autoantibodies (cANCA)

General information

c-ANCA's are directed to proteinase 3 and are typically associated with Wegener's granulomatosis. Also see section on ANCA.

Specimen transport: At room temperature

Repeat frequency: Used to monitor response to treatment and risk of relapse

Special precautions: None

Laboratory information

Normal range: <0.9 AI

Volume and sample type: 7ml clotted blood

Method: Multiplex flow immunoassay

Turnaround time (calendar days from sample receipt to authorised result): Median - 1, 95th percentile - 8

Clinical information

Indications for the test: Suspected Wegener's granulomatosis and monitoring treatment

Factors affecting the test: None

 

Clinical workstation reference: PR3

 

(Last updated October 7th 2014)