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Voltage-Gated Potassium Channel Antibodies

Referred to:

Department of Immunology
The Churchill Hospital
Old Road

General information

Specimen transport: At room temperature

Repeat frequency: significant change of clinical symptoms

Special precautions: None

Laboratory information

Normal reference range: 0-100 pmol

Volume and sample type: 7ml clotted blood

Method: RIA

Turnaround time (calendar days from sample receipt to authorised result): Median - 16, 95th percentile - 34

Clinical information

Indications for the test: Peripheral nerve hyperexcitability, neuromyotonia, Morvan's syndrome.

Factors affecting the test: Approx 20% of patients with VGKC antibodies will have an underlying thymoma. Patients may have Myasthenia gravis with or without acetylcholine receptor antibodies.


ICE reference: Anti VGKC Antibodies


(Last updated May 29th 2018)