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Bronchopulmonary aspergillosis, Aspergilloma and Hypersensitivity pneumonitis

This section deals with the clinical conditions bronchopulmonary aspergillosis, aspergilloma and hypersensitivity pneumonitis, listing the relevant immunological tests, together with a short explanation of their use.

Relevant immunological tests: Aspergillus precipitins

In bronchopulmonary aspergillosis and aspergilloma a mixture of IgE and IgG antibodies are usually present. Bronchopulmonary aspergillosis can be caused by species other than A. fumigatus.

In allergic rhinitis and asthma, where aspergillus is the relevant allergen, IgE antibodies dominate.

In hypersensitivity pneumonitis, IgG antibodies are usually present alone. IgG antibodies, without IgE antibodies can also be seen in some cases of sub acute invasive aspergillosis.

IgG antibodies are infrequent in healthy individuals.

Aspergillus antibodies are not a recommended test for the investigation of the majority of cases of invasive aspergillosis in immunocompromised hosts.


(Last updated October 8th 2014)