Coeliac disease
This section deals with the clinical condition coeliac disease
(gluten sensitive enteropathy GSE), listing the relevant
immunological tests, together with a short explanation of their
use.
Patient information is available from the Coeliac Society.
Relevant immunological tests:
IgA antibodies to tissue transglutaminase are found in active
coeliac disease, and can be used to monitor compliance with
treatment. Similar antibodies are seen in dermatitis
herpetiformis.
We may have to measure IgA to ensure that IgA deficiency
(particularly common in these patients) is not causing a false
negative result. IgG antibodies to tissue transglutaminase are
utilized in IgA deficient patients.
(Last updated October 8th
2014)