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Coeliac disease

This section deals with the clinical condition coeliac disease (gluten sensitive enteropathy GSE), listing the relevant immunological tests, together with a short explanation of their use.

Patient information is available from the Coeliac Society.

Relevant immunological tests:

IgA antibodies to tissue transglutaminase are found in active coeliac disease, and can be used to monitor compliance with treatment. Similar antibodies are seen in dermatitis herpetiformis.

We may have to measure IgA to ensure that IgA deficiency (particularly common in these patients) is not causing a false negative result. IgG antibodies to tissue transglutaminase are utilized in IgA deficient patients.


(Last updated October 8th 2014)