This section deals with secondary immunodeficiency, listing the
relevant immunological tests, together with a short explanation of
Relevant immunological tests:
Secondary causes of immunodeficiency are more common than
primary causes and levels of immunoglobulins might reflect
decreased production (eg. lymphoproliferative disorders, drugs) or
increased losses (nephritic syndrome).
In HIV infection the CD4 count is used to monitor progress of
disease and inform treatment decisions. Other acute and chronic
diseases affect CD4 counts.
In HIV infection they are best done at the same time of day each
time and avoiding acute ill health. They should never be done as a
substitute to HIV antibody testing to diagnose HIV infection.
Guidelines and information on CD4 counts are available from Aidsmap.
Additional patient information is available
(Last updated October 8th