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Thyroid goitre/nodule, hypo/hyperthyroidism

This section deals with the clinical condition thyroid goitre/nodule, hypo/hyperthyroidism, listing the relevant immunological test, together with a short explanation of its use.

Relevant immunological test: Ab to thyroid peroxidase (TPO)

The levels of antibodies to thyroid peroxidase are closely related to the degree of lymphocytic infiltration in the thyroid. They are raised in autoimmune thyroiditis (90% of hypo-, >60% of hyper-) and both in post-viral and post-partum thyroiditis. They are less frequently raised in thyroid neoplasia/nodules/cysts, but their presence does not exclude these conditions.

 

(Last updated October 8th 2014)