We use cookies to help us improve the website and your experience using it. You may delete and block all cookies from this site at any time. However, please note this may result in parts of the site no longer working correctly. If you continue without changing your settings we will assume you are happy to receive all cookies on this site.


Systemic Lupus Erythematosus

This section deals with the clinical condition systemic lupus erythematosus, listing the relevant immunological tests, together with a short explanation of their use.

Relevant immunological tests:

Criteria for the diagnosis of SLE include antinuclear antibodies (ANA), antibodies to ds DNA, (Crithidia assay if appropriate) antibodies to extractable nuclear antigens (ENA) and anti cardiolipin antibodies.

The presence of particular groups of serum antibodies may be associated with different clinical patterns of disease activity.

Other typical immunological findings include raised serum IgG, and low serum complement levels (C3, C4) as well as the presence of rheumatoid factor, and other autoantibodies.

DNA antibody levels, C4 levels (and ESR) are of some help in monitoring disease activity.


(Last updated October 9th 2014)