Small vessel hypersensitivity vasculitis
This section deals with the clinical condition small vessel
hypersensitivity vasculitis, listing the relevant immunological
tests, together with a short explanation of their use.
Relevant immunological tests:
Infection, drugs, foreign proteins (as examples) may be causal
factors in a vasculitis affecting predominantly the skin.
Immunological findings may sometimes include raised ESR/CRP,
depressed levels of complement factors suggesting consumption, and
the presence of antinuclear antibodies and rheumatoid factor (low
General screening tests for vasculitis should also include serum
immunoglobulins, and ANCA.
If there is evidence for more extensive visceral involvement,
one of the primary systemic
vasculitides may be involved.
Alternatively, the vasculitis may be secondary to autoimmune
disease (eg. SLE, chronic active hepatitis), neoplasia (eg.
lymphoma), cryoglobulinaemia (these are immunoglobulins that form
precipitates in the cold).
(Last updated October 9th 2014)