Maldi-TOF instrument will mean faster patient diagnosis
CMFT's Microbiology department has taken delivery of a Bruker
matrix assisted laser desorption/ionisation time of flight mass
spectrometry - or Maldi-TOF - instrument, funded through Public
This is an important step for the laboratory as part of an
on-going automation programme and is one of the latest tools for
the study of microorganisms.
The introduction of the Maldi-TOF will mean significant time
savings and faster effective patient diagnosis.
Over the last 80 years Diagnostic Microbiology has utilised
biochemical and sugar reactions to identify species and subspecies
of micro-organisms-which can be a time consuming process.
The Maldi-TOF enables identification and taxonomic
classification of organisms direct from culture plates without the
need for further incubation or biochemical tests.
Proteomic fingerprints are compared with reference spectra in
the Maldi-TOF library and the instrument provides a result in less
time than conventional culture techniques, which is great news for
A team from Microbiology has been busy validating the instrument
and everyone involved feels this is an exciting and innovative step
forward for the department.
The Maldi-TOF has already proved to be an invaluable diagnostic
tool and staff are looking forward to carrying out some interesting
research projects in the future.