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Gastric Biopsies for Helicobacter pylori (Bacteriology)

General information

Collection container (including preservatives): CE marked leak proof containerin a sealed plastic bag. The biopsy should be placed in a small, sterile container such as a bijou bottle, containing a small amount (approximately 100┬ÁL) of sterile isotonic saline to preserve moisture.

Specimen type: Gastric biopsies - This is the specimen of choice for the culture of H. pylori

Collection: Before antimicrobial therapy where possible

Gastric biopsy specimens are usually taken from the gastric antrum at endoscopy, and sometimes from the body depending on location of inflammation

Specimen transport: Specimens should be transported and processed as soon as possible (preferably within 6h)

Minimum volume of sample: At the discretion of the endoscopist as it depends on the individual patient

Special precautions: It is important to maintain a moist atmosphere during transport.

Laboratory information

Measurement units: Not applicable

Biological reference units: Not applicable

Turnaround time: Culture result within 10 days

Clinical information

Clinical decision points: Not applicable

Factors known to significantly affect the results: Sensitivity of the microscopy may be reduced if the biopsy is submerged in the saline, because mucus globules form and production of a satisfactory smear becomes difficult.


(Last reviewed October 24th 2017)