Trial aims to diagnose diabetes in young people
A screening programme that can detect type 1 diabetes up to ten
years before symptoms are visible has recently launched in Greater
Trialnet is a network of 18 clinical centres with more than 200
screening site throughout the world. The network is dedicated to
the study, prevention and early treatment of type 1 diabetes.
TrialNet is supported by other major diabetes organisations
including the Juvenile Diabetes Research Foundation International,
National Institute of Health Research, Medicines for Children
Research Network and the Wellcome Trust, which is based at Royal
Manchester Children's Hospital.
The rate of type 1 diabetes is rising worldwide, with the
greatest increases seen in children under the age of five. There is
no proven way to slow down or prevent Type 1 diabetes, but it is
thought that identifying those with the condition means they can be
closely monitored and join research studies testing for ways to
delay or treat the condition.
Dr Ian Doughty, a paediatric consultant at Royal Manchester
Children's Hospital said, "This is an important study looking at
how Type 1 diabetes develops and what can be done to prevent it. It
is a study that's taking place worldwide, so it is very good that
families from Manchester and the North West can be involved. I hope
that as many people as possible who think they could be at risk of
type 1 diabetes take the opportunity to be screened for the
TrialNet offers a simple blood test that can identify if a
person has an increased risk for Type 1 diabetes up to ten years
before symptoms appear. The symptoms of diabetes can appear
suddenly but research suggests that the potential risk can be
detected years before these symptoms appear, creating a window of
opportunity when measures can be taken to attempt to delay or
prevent the disease. Early diagnosis makes it possible to avoid
dangerous complications that can occur when diabetes goes
undetected. It may also help the body make insulin for a longer
period of time.
The blood test looks for certain markers in the blood (called
autoantibodies) which signal an increased risk of the disease. For
relatives of people with Type 1 diabetes, only five out of 100 will
have these markers.
Screening is offered to those aged 45 and under, who have a
parent, brother, sister or child with type 1 diabetes and those
aged 18 and under with a niece, nephew, aunt, uncle, grandparent,
half-brother, half-sister or cousin with type 1 diabetes. Those
testing negative for the disease will have the opportunity to be
screened every year until they are 18.
Screening is currently taking place at Royal Manchester
Children's Hospital, and it is hoped that more sites will be soon
be able to offer the test.
Notes to editors
For more information about TrialNet, please ask your GP or
contact 0800 634 0102 or email firstname.lastname@example.org
More information about type 1 diabetes:
- Also known as insulin dependent diabetes (IDDM) or juvenile
- Usually develops before the age of 30 and requires insulin
- Autoimmune condition which destroys the cells in the pancreas
which produce insulin