One year on: Major success for Children’s Clinical Research Facility
The Wellcome Trust Children's Clinical Research Facility
at the Royal Manchester Children's Hospital has had overwhelming
success since opening in November 2009, with the aim of testing new
medicines in children and young adults to make sure that they are
safe and effective.
The facility is the first of its kind in the North West and one
of only a small number of dedicated paediatric research facilities
across the UK. To mark the one year anniversary, a 1st birthday
party was thrown this on November 17th 2010, for the children,
families and researchers who have been involved in studies over the
One clinical research study participant is 17 year-old Ambreen
Yasin. When Ambreen was 15, her GP told her she was at risk of
developing type 2 diabetes. She then went on to take part in a
clinical trial looking at the effects of a drug called metformin in
children and adolescents who had too much insulin in their bodies
and were unable to properly regulate blood sugar.
The study aimed to find out whether treatment with metformin
reduced a child's body mass index and improve the ability to
regulate blood sugar.
Speaking of the study, Ambreen said: "I was a bit nervous at
first and didn't really know what to expect, but the nurses were
great and explained everything that would happen.
"I had to take a tablet up to three times a day for six
months. I feel quite proud for taking part in something
that hopefully will bring new information and could possibly change
many lives. I discovered a whole new side to science and
medicine and realised how important the trials were."
Dr Nicholas Webb, the facility's director, said: "When the
new children's clinical research facility opened last year, we had
high hopes for its success. The reality has far exceeded our
expectations and we are delighted with the results. So much so that
in order to cope with demand we have doubled our nursing team from
five to ten. Our facility is testing medicines of the future, so
that children and young adults can benefit from improved available
"Ambreen has been fantastic for taking part in this
study", Dr Webb added. "It is only through children and
their families agreeing to take part in clinical research that we
are able to continue our excellent work that will ultimately
benefit many more children worldwide."
More information about the Wellcome Trust Children's Clinical
Research Facility can be found online at www.childrenscrf.org.