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Clinical Immunology

Welcome to Manchester Royal Infirmary Immunology service. We offer a comprehensive service for the diagnosis and management of patients with primary immunodeficiencies. In order to be seen in our clinic a referral from a General Practitioner or Specialist is required. For information on how to refer please see the contact details section below.

The warning signs of possible primary immunodeficiency include any 2 or more of the following:

Four or more new ear infections within 1 year

Two or more serious sinus infections within 1 year

Two or more months on antibiotics with little effect

Two or more pneumonias within 1 year

Failure of an infant to gain weight or grow normally

Recurrent, deep skin or organ abscesses

Persistent thrush in mouth or elsewhere on skin

Need for intravenous antibiotics to clear infections

Two or more deep-seated infections

A family history of primary immune deficiency


The immunology services provided includes:

  • Diagnosis and assessment of patients with suspected immunodeficiency
  • Home training for immunoglobulin replacement therapy
  • Diagnosis and management of patients with hereditary and acquired angioedema including home therapy training (C1 inhibitor and icatibant therapy)
  • Close links with colleagues from respiratory medicine, ENT, rheumatology, haematology/oncology, nephrology, dermatology and anaesthesia
  • We work closely with our paediatric colleagues to provide a safe and effective transition service.

Outpatient Service




Monday am

Allergy (new and follow up)

Main OPD Suite D


Tuesday am (Every 2nd week)

Anaesthetic anaphylaxis (new and follow up)

Elective Treatment Centre


Tuesday am

Infusion day case

Specialist Medicine Day Unit


Challenge Day Case

Specialist Medicine Day Unit


Tuesday pm

Immunodeficiency (follow up only)

Ward 44 Haematology Out Patients


Wednesday pm

Allergy (new and follow up)

Main OPD Suite A


Thursday am

Allergy (new and follow up)

Main OPD Suite D



Main OPD Suite D


Thursday pm

Allergy (new and follow up)

Main OPD Suite D


Friday am

Immunodeficiency (new and follow up)

Kellgren Centre for Rheumatology


Friday all day - (approx every 2 weeks)

Challenge Day Case

Specialist Medicine Day Unit



Clinics are weekly unless otherwise specified.

Home Care

Most patients requiring immunoglobulin replacement therapy are on treatment subcutaneously delivered at home, either as self infusion or as assisted home care with a trained nurse. The Immunology nursing team run the home care programme, training and monitoring these patients. They also conduct annual and as required assessments to resolve any technical difficulties that may arise. They also train patients for self-treatment with C1 esterase inhibitor and icatibant.


The Department has an active research profile.

The department coordinates the UK Primary Immunodeficiency registry (Catherine Bangs is the national coordinator for the UK registry, supported by Stephanie Farrell) and the European Society of Immunodeficiencies patient registry in which Manchester has the fourth largest group of PID patients in the UK.

The department also participates in surveillance studies of patients with hereditary angioedema and colaborates on the PID-Bridge study. The department is recruiting patients into a study of a novel oral medication for hereditary angioedema.

There are often active observational studies and clinical trials within the department and we strive to offer all our patients the opportunity to participate in clinical research, although you are of course free to decline at any point. Please feel free to ask your consultant for details on potential research studies.

Education and Training

The Department is actively involved in the delivery of educational sessions for Primary and Secondary care providers. If you are interested in learning more about Immunology/Allergy please contact us.

The Department actively trains junior doctors and registered nurses for specialist roles within Immunology.


Department of Allergy and Immunology Manchester Royal Infirmary Oxford Road Manchester M13 9WL
Click here for directions to the Hospital

Contact Details:

Administration: 0161 276 6468 Fax: 0161 276 6439 Specialist Nurses: 0161 276 6186

Referrals can be sent by post, email (from primary care and other trusts using nhs.net to send: cmm-tr.Immunology-referrals@nhs.net or from internal CMFT staff using cmft.nhs.uk to send: Clinical.Immunology@cmft.nhs.uk) or fax.

Clinical enquiries and queries can be sent by email also (the above addresses) from health care professionals. Please remember not to use patient identifiable information unless sending via nhs.net to nhs.net or cmft.nhs.uk to cmft.nhs.uk.

Patients can contact us by Email but need to read the disclaimer by following the Email link first.

Additional Support:

The specialist nurses provide support and telephone advice to patients once they have been accepted for care in the department



Tomaz Garcez - Consultant Clinical Immunologist and Clinical Head of Service

Sara Drinkwater - Consultant Clinical Immunologist (Part time)

Specialist Nurses

Alex Farragher

Jill Edmonds

Jennifer Osborne

Peter Pimblett

Study Coordinators

Catherine Bangs

Trainee and other doctors

Speciality trainee doctor (Immunology)
Foundation Year 2 Doctor in Training

Administrative Staff

Angela Bedford
Josephine Hopkinson
Julie Redshaw