Retrograde semen analysis
Retrograde ejaculation is a condition where semen is ejaculated
backwards into the bladder. Some patients may be able to
produce semen if masturbation takes place whilst the bladder is
full. However, if this is not possible, it is necessary to
make the urine alkaline (neutralise the acidity), and then to
extract the sperm from urine passed after masturbation.
Sodium bicarbonate (bicarbonate of soda) is prescribed to
try to achieve an alkaline pH of approximately 7.5 in the
urine. If you are undergoing investigation for retrograde
ejaculation your clinician will provide you with instructions on
how to prepare for the test.
Factors that may affect Retrograde semen analysis
If the pH of the urine was not within the range of 7.5-8.5.
If the sample is not produced 45 minutes after the patient has
taken the Sodium bicarbonate.
If the urine is not examined within 5 minutes of being
Updated Sept 2014.